STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1106Protein of unknown function DUF2344; COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: afw:Anae109_0737 radical SAM domain-containing protein; PFAM: Protein of unknown function DUF2344; SPTR: Radical SAM domain protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344). (331 aa)    
Predicted Functional Partners:
Isop_1108
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032: IPR005698; KEGG: gau:GAU_1482 phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
       0.788
Isop_1107
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
       0.786
Isop_0315
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197: IPR006638; KEGG: rba:RB5334 Fe-S oxidoreductase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase; PFAM: Radical SAM superfamily.
 
    0.785
Isop_1105
KEGG: lch:Lcho_2901 hypothetical protein; SPTR: Helicase.
       0.773
Isop_1104
Ribonuclease, Rne/Rng family; COGs: COG1530 Ribonuclease G and E; InterPro IPR003029: IPR004659: IPR019307; KEGG: psl:Psta_2436 ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; SPTR: Ribonuclease, Rne/Rng family; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.
       0.516
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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