Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1132Peptidase M50; InterPro IPR008915; KEGG: sno:Snov_3348 peptidase M50; PFAM: peptidase M50; SPTR: Putative uncharacterized protein; manually curated; PFAM: Peptidase family M50. (413 aa)    
Predicted Functional Partners:
Isop_1131
Homocysteine S-methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: ade:Adeh_1778 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: Homocysteine S-methyltransferase; PFAM: Homocysteine S-methyltransferase.
       0.777
Isop_1764
Peptidase M50; InterPro IPR008915; KEGG: plm:Plim_2044 peptidase M50; PFAM: peptidase M50; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M50.
  
     0.766
Isop_1130
Protein of unknown function UPF0153; InterPro IPR005358; KEGG: plm:Plim_3260 hypothetical protein; PFAM: protein of unknown function UPF0153; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153).
 
     0.676
Isop_1133
COGs: COG2154 Pterin-4a-carbinolamine dehydratase; InterPro IPR001533; KEGG: plm:Plim_4232 transcriptional coactivator/pterin dehydratase; PFAM: transcriptional coactivator/pterin dehydratase; SPTR: Probable pterin-4-alpha-carbinolamine dehydratase; PFAM: Pterin 4 alpha carbinolamine dehydratase.
       0.406
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.