Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_1138GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: rer:RER_23190 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (275 aa)    
Predicted Functional Partners:
Isop_2646
Dual specificity protein phosphatase; InterPro IPR000387: IPR000340; KEGG: olu:OSTLU_7942 predicted protein; PFAM: Dual specificity protein phosphatase; SPTR: Predicted protein; PFAM: Dual specificity phosphatase, catalytic domain.
  
     0.739
Isop_2419
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR003587: IPR006530: IPR006141; KEGG: plm:Plim_1036 AmoP; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: AmoP; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).
  
     0.689
Isop_3202
Hypothetical protein; KEGG: ttu:TERTU_3103 putative type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.686
Isop_3082
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680: IPR019782: IPR017986: IPR019781; KEGG: hoh:Hoch_3099 serine/threonine protein kinase with WD40 repeats; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: WD domain, G-beta repeat.
  
     0.663
Isop_1833
CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein, GSU0054 family.
  
     0.646
Isop_0604
phospholipase/Carboxylesterase; InterPro IPR003140; KEGG: sus:Acid_1148 putative esterase; PFAM: phospholipase/Carboxylesterase; SPTR: Putative esterase; PFAM: Phospholipase/Carboxylesterase.
  
     0.634
Isop_0601
KEGG: sus:Acid_4318 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.603
Isop_1005
Protein of unknown function DUF1464; COGs: COG2441 butyrate kinase; InterPro IPR009927; KEGG: pfu:PF1187 hypothetical protein; PFAM: protein of unknown function DUF1464; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1464).
  
     0.489
Isop_1834
CRISPR-associated protein, Csx4 family; InterPro IPR013403; KEGG: hoh:Hoch_4848 CRISPR-associated protein GSU0053; PFAM: CRISPR-associated protein GSU0053; SPTR: CRISPR-associated protein GSU0053; PFAM: CRISPR-associated protein GSU0053 (Cas_GSU0053); TIGRFAM: CRISPR-associated protein, GSU0053 family, N-terminal domain.
  
     0.487
Isop_0455
KEGG: cat:CA2559_07901 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.477
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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