Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1147Amino acid/peptide transporter; COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR005279: IPR000109: IPR018456; KEGG: xal:XALc_Yp01 hypothetical amino acid/peptide transporter protein; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: Di-/tripeptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial. (629 aa)    
Predicted Functional Partners:
Isop_0088
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
  
    0.532
Isop_1883
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28.
 
 
   0.530
Isop_1654
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR000834: IPR002469; KEGG: sus:Acid_5302 peptidase S9B dipeptidylpeptidase IV subunit; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: Peptidase S9B, dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region; Zinc carboxypeptidase.
  
    0.483
Isop_0484
Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1.
  
 
 0.461
Isop_0972
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: nde:NIDE3566 putative peptidase; PFAM: peptidase M28; SPTR: Aminopeptidase; PFAM: Peptidase family M28.
 
 
   0.447
Isop_3575
COGs: COG0531 Amino acid transporter; InterPro IPR002293: IPR004841; KEGG: gau:GAU_2006 putative permease; PFAM: amino acid permease-associated region; SPTR: Putative permease; PFAM: Amino acid permease.
  
 
 
 0.418
Isop_3049
Major facilitator superfamily MFS_1; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: gem:GM21_2012 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
  
     0.408
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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