STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_1160Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734: IPR013026: IPR001440; KEGG: azl:AZL_f01560 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. (652 aa)    
Predicted Functional Partners:
Isop_0878
Hypothetical protein; InterPro IPR017481; KEGG: nca:Noca_3554 TPR repeat-containing protein; SPTR: TPR repeat; TIGRFAM: conserved hypothetical protein TIGR03032.
  
   0.903
Isop_3640
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR010227: IPR001750: IPR003918; KEGG: psl:Psta_0731 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
    
 
 0.784
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.783
Isop_0191
KEGG: xcb:XC_0878 protein kinases, catalytic domain; region: PKc_like; cl09925; SPTR: Putative uncharacterized protein.
   
 0.778
Isop_1293
COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR011506: IPR001343; KEGG: psl:Psta_1955 peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; Planctomycete extracellular domain protein; Hemolysin-type calcium-binding region; SPTR: Peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
   
   0.765
Isop_1521
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.765
Isop_3676
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG0457 FOG: TPR repeat; InterPro IPR019734: IPR013026: IPR001440; KEGG: pcs:Pc22g03720 Pc22g03720; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Pc22g03720 protein; PFAM: Tetratricopeptide repeat.
 
 
 0.757
Isop_0125
InterPro IPR019734: IPR013026: IPR001440; KEGG: cyb:CYB_1571 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Tetratricopeptide repeat protein.
 
   0.702
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
  
 0.649
Isop_1162
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: nde:NIDE2987 putative glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1.
 
   0.608
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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