Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1220Protein of unknown function DUF1080; InterPro IPR010496; KEGG: rba:RB9196 secreted glycosyl hydrolase; PFAM: protein of unknown function DUF1080; SPTR: Probable secreted glycosyl hydrolase; PFAM: Domain of Unknown Function (DUF1080). (406 aa)    
Predicted Functional Partners:
Isop_2174
InterPro IPR010496; KEGG: psl:Psta_3759 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative large multi-functional protein; PFAM: Domain of Unknown Function (DUF1080).
  
    0.776
Isop_0757
InterPro IPR010496; KEGG: caa:Caka_0473 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
    0.774
Isop_2477
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_0037 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.758
Isop_3701
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_2857 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.749
Isop_0462
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311; KEGG: plm:Plim_1207 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.745
Isop_3354
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311: IPR017909: IPR000683; KEGG: sli:Slin_6215 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable NADH-dependent dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.737
Isop_1075
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683; KEGG: plm:Plim_0006 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.734
Isop_2907
InterPro IPR011701; KEGG: psl:Psta_3978 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
  
     0.725
Isop_3280
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683; KEGG: zpr:ZPR_3683 putative dehydrogenase and relate protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.719
Isop_2526
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_3510 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.715
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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