STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
Isop_1222COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: mca:MCA0477 allophanate hydrolase, subunit 2; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; SPTR: Allophanate hydrolase, subunit 2; PFAM: Allophanate hydrolase subunit 2. (334 aa)    
Predicted Functional Partners:
Isop_0464
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833; KEGG: nde:NIDE1154 putative allophanate hydrolase subunit 1; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Putative uncharacterized protein; PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
 
 
 0.992
Isop_0463
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
  
 0.931
Isop_0121
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
Isop_0306
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: gau:GAU_2335 gamma-glutamyltranspeptidase precursor; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
  0.900
Isop_1457
Glutamate--cysteine ligase; COGs: COG3572 Gamma-glutamylcysteine synthetase; InterPro IPR006336; KEGG: nml:Namu_1082 glutamate/cysteine ligase family protein; PFAM: glutamate--cysteine ligase GCS2; PRIAM: Glutamate--cysteine ligase; SPTR: Glutamate/cysteine ligase family protein; PFAM: Glutamate-cysteine ligase family 2(GCS2); TIGRFAM: glutamate--cysteine ligase, plant type.
     
  0.900
Isop_2261
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: aba:Acid345_3078 gamma-glutamyltransferase 2; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase 2. Threonine peptidase. MEROPS family T03; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
  0.900
Isop_2214
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
 
  0.826
Isop_0061
COGs: COG0174 Glutamine synthetase; InterPro IPR004809: IPR008147: IPR008146; KEGG: psl:Psta_1754 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
     
 0.808
Isop_1282
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097: IPR006096: IPR006095: IPR014362; KEGG: ath:AT5G18170 GDH1 (GLUTAMATE DEHYDROGENASE 1); ATP binding / glutamate dehydrogenase [NAD(P)+]/ oxidoreductase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Putative uncharacterized protein; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
  0.801
Isop_0123
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR002872: IPR015590; KEGG: psl:Psta_0870 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: 1-pyrroline-5 carboxylate dehydrogenase; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Belongs to the aldehyde dehydrogenase family.
     
  0.800
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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