STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_1244Xylose isomerase domain-containing protein TIM barrel; COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR006311: IPR012307; KEGG: zpr:ZPR_4222 probable glyoxylate-induced protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Probable glyoxylate-induced protein; PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family. (303 aa)    
Predicted Functional Partners:
Isop_2183
COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR012307; KEGG: cag:Cagg_1301 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Hydroxypyruvate isomerase; SPTR: Xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase-like TIM barrel.
  
  
 
0.920
Isop_0682
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: mta:Moth_1954 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
   
 
  0.901
Isop_3726
Alanine-glyoxylate aminotransferase apoenzyme; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR020578: IPR000192; KEGG: psl:Psta_2949 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
     
  0.900
Isop_1243
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR006311: IPR000683; KEGG: dfe:Dfer_1237 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
 
    0.751
Isop_0462
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311; KEGG: plm:Plim_1207 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
 
    0.744
Isop_2477
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_0037 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
    0.741
Isop_2174
InterPro IPR010496; KEGG: psl:Psta_3759 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative large multi-functional protein; PFAM: Domain of Unknown Function (DUF1080).
 
     0.702
Isop_0757
InterPro IPR010496; KEGG: caa:Caka_0473 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
 
     0.680
Isop_3665
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: dfe:Dfer_4144 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable NADH-dependent dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
 
    0.668
Isop_3701
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_2857 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
    0.665
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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