Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1250Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: dde:Dde_0462 sulfatase; PFAM: sulfatase; SPTR: Sulfatase, putative; PFAM: Sulfatase. (530 aa)    
Predicted Functional Partners:
Isop_1428
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: htu:Htur_3376 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase.
  
     0.774
Isop_2726
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: psl:Psta_2900 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase.
  
     0.770
Isop_3638
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: sli:Slin_1433 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.613
Isop_1251
UspA domain-containing protein; COGs: COG0531 Amino acid transporter; InterPro IPR006016; KEGG: pcu:pc0262 hypothetical protein; PFAM: UspA domain-containing protein; SPTR: Amino acid permease-associated region; PFAM: Universal stress protein family.
  
    0.484
Isop_1249
KEGG: ddr:Deide_06010 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2721).
       0.464
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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