Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_1257Amidohydrolase 3; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR013108; KEGG: swi:Swit_0080 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Putative uncharacterized protein; PFAM: Amidohydrolase family. (427 aa)    
Predicted Functional Partners:
Isop_1259
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: rmr:Rmar_1420 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
     0.873
Isop_1256
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: tpd:Teth39_1750 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
    
0.841
Isop_1262
Amidohydrolase 3; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR013108: IPR006680; KEGG: sth:STH1913 putative amidohydrolase; PFAM: Amidohydrolase 3; amidohydrolase; SPTR: Putative amidohydrolase; PFAM: Amidohydrolase family.
 
     0.837
Isop_3297
InterPro IPR000834; KEGG: sus:Acid_1533 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SPTR: Peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase.
  
     0.678
Isop_0161
KEGG: cpi:Cpin_1010 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.648
Isop_1258
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: dau:Daud_2020 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
    
0.623
Isop_1261
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: tte:TTE0530 imidazolonepropionase and related amidohydrolase; PFAM: amidohydrolase; SPTR: Imidazolonepropionase and related amidohydrolases; PFAM: Amidohydrolase family.
 
    
0.623
Isop_1260
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: ami:Amir_0524 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
    
0.622
Isop_2231
COGs: COG0308 Aminopeptidase N; KEGG: rba:RB5627 aminopeptidase; SPTR: Putative aminopeptidase; PFAM: Peptidase family M1.
  
     0.600
Isop_1644
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: rmr:Rmar_0910 glycosyl hydrolase BNR repeat-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Glycosyl hydrolase BNR repeat-containing protein; PFAM: BNR/Asp-box repeat.
 
     0.488
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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