STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
Isop_1293COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR011506: IPR001343; KEGG: psl:Psta_1955 peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; Planctomycete extracellular domain protein; Hemolysin-type calcium-binding region; SPTR: Peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD. (740 aa)    
Predicted Functional Partners:
Isop_1517
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021: IPR001650: IPR014014: IPR000629: IPR 014001: IPR011545; KEGG: psl:Psta_1620 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
 
 
 0.845
Isop_2789
ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterProIPR014021: IPR001650: IPR014001: IPR007502: IPR 013689: IPR010225; KEGG: psl:Psta_3120 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase domain protein; helicase-associated domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpB.
  
 0.832
Isop_2003
KR domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014031: IPR014043: IPR006163: IPR013968: IPR 009081; KEGG: glo:Glov_2267 polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; SPTR: Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: acyl carrier protein.
   
 
 0.781
Isop_1160
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734: IPR013026: IPR001440; KEGG: azl:AZL_f01560 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
   
   0.765
Isop_2700
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099; KEGG: psl:Psta_1619 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disul [...]
    
 
 0.750
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
  
 
 0.728
Isop_0219
ATP-binding region ATPase domain protein; COGs: COG0326 Molecular chaperone HSP90 family; InterPro IPR001404: IPR020575: IPR003594; KEGG: lic:LIC12469 HSP90 family protein; PFAM: ATP-binding region ATPase domain protein; SPTR: HtpG; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 0.718
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.718
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.714
Isop_2908
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: cag:Cagg_1601 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Histone deacetylase superfamily; PFAM: Histone deacetylase domain.
   
 0.694
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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