Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Isop_1315Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: nmu:Nmul_A2462 rhomboid-like protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; PFAM: Rhomboid family. (694 aa)    
Predicted Functional Partners:
Isop_1314
Gas vesicle synthesis GvpLGvpF; InterPro IPR009430; KEGG: mxa:MXAN_2772 GvpL/GvpF family gas vesicle protein; PFAM: Gas vesicle synthesis GvpLGvpF; SPTR: Gas vesicle protein, GvpL/GvpF family; PFAM: Gas vesicle synthesis protein GvpL/GvpF.
       0.592
Isop_1316
InterPro IPR000352; KEGG: plm:Plim_0816 class I peptide chain release factor; PFAM: Class I peptide chain release factor; SPTR: Putative uncharacterized protein; PFAM: RF-1 domain.
       0.542
Isop_0687
InterPro IPR003369; KEGG: plm:Plim_2724 twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Putative Sec-independent protein translocase component; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family.
   
 
 0.468
tatA
Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.468
Isop_2833
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: rxy:Rxyl_1321 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; manually curated; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
  
  
 0.433
Isop_2124
Metal dependent phosphohydrolase; COGs: COG3481 HD-superfamily hydrolase; InterPro IPR003607: IPR006674; KEGG: psl:Psta_4761 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Nucleic acid-binding protein, putative; PFAM: HD domain.
  
     0.412
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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