STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1317Na-Ca exchanger/integrin-beta4; InterPro IPR003644: IPR000169: IPR006626; KEGG: hau:Haur_4998 Na-Ca exchanger/integrin-beta4; PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; Parallel beta-helix repeat; SPTR: Na-Ca exchanger/integrin-beta4; PFAM: Calx-beta domain. (4765 aa)    
Predicted Functional Partners:
Isop_3404
Hypothetical protein; InterPro IPR018247; KEGG: hwa:HQ1193A cell surface glycoprotein; SPTR: Probable cell surface glycoprotein; PFAM: Subtilase family.
  
     0.489
Isop_0635
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0348 Polyferredoxin; InterPro IPR017896: IPR017900; KEGG: hoh:Hoch_0561 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain.
  
  
 0.451
Isop_2330
FG-GAP repeat protein; InterPro IPR013519: IPR013517; KEGG: noc:Noc_2093 integrins alpha chain; PFAM: FG-GAP repeat protein; SMART: Integrin alpha beta-propellor repeat protein; SPTR: Integrins alpha chain.
  
     0.448
Isop_3257
KEGG: smd:Smed_1270 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.442
Isop_2500
Peptidase M10A and M12B matrixin and adamalysin; InterPro IPR001818: IPR021190; KEGG: hwa:HQ1193A cell surface glycoprotein; PFAM: peptidase M10A and M12B matrixin and adamalysin; SPTR: Probable cell surface glycoprotein; PFAM: Matrixin.
  
     0.440
Isop_2275
InterPro IPR001623; KEGG: tcu:Tcur_1396 fibronectin type III domain protein; PFAM: heat shock protein DnaJ domain protein; SPTR: Fibronectin type III domain protein.
 
  
 0.425
Isop_1316
InterPro IPR000352; KEGG: plm:Plim_0816 class I peptide chain release factor; PFAM: Class I peptide chain release factor; SPTR: Putative uncharacterized protein; PFAM: RF-1 domain.
       0.418
Isop_3427
Hypothetical protein; InterPro IPR022272; KEGG: psl:Psta_2388 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.416
Isop_0596
Hypothetical protein; KEGG: rpt:Rpal_2847 alginate O-acetyltransferase AlgJ; SPTR: Alginate O-acetyltransferase AlgJ.
 
  
 0.415
Isop_0054
Multi antimicrobial extrusion protein MatE; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002528; KEGG: gbm:Gbem_1791 polysaccharide biosynthesis protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
 
     0.413
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.