Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1357Hypothetical protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003439: IPR017940: IPR006162; KEGG: cpe:CPE1525 ABC transporter; SPTR: Phospholipid-lipopolysaccharide ABC transporter. (685 aa)    
Predicted Functional Partners:
Isop_2119
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593: IPR017871: IPR003439; KEGG: gau:GAU_2113 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter-related protein; PFAM: ABC transporter.
   
0.722
Isop_2003
KR domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014031: IPR014043: IPR006163: IPR013968: IPR 009081; KEGG: glo:Glov_2267 polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; SPTR: Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: acyl carrier protein.
   
 0.660
Isop_1421
ABC transporter related protein; COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterProIPR003439: IPR017940: IPR005074: IPR001140: IPR 017871: IPR003593; KEGG: npu:Npun_F3763 ABC transporter related; PFAM: ABC transporter related; peptidase C39 bacteriocin processing; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: Peptidase C39 family; ABC transporter transmembrane region; ABC transporter; TIGRFAM: NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein; NHPM b [...]
 
 
  
0.622
Isop_3139
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR018181: IPR001023: IPR013126; KEGG: nhl:Nhal_2517 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70; PFAM: Hsp70 protein.
  
  0.604
Isop_0425
AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003338: IPR004201: IPR003959: IPR003593: IPR 003960: IPR005938; KEGG: mxa:MXAN_2773 AAA family ATPase; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: ATPase, AAA family; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: ATPase family associated with various cellular activities (AAA); Cell division protein 48 (CDC48), N-terminal domain; Cell division protein 48 (CDC48), domain 2; [...]
   
 0.601
Isop_0076
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR001023: IPR018181: IPR013126; KEGG: cac:CA_C0472 HSP70/DnaK family protein; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; PFAM: Hsp70 protein.
  
  0.589
Isop_1041
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR002035: IPR013126: IPR001023: IPR018181; KEGG: cac:CA_C0473 heat shock protein DnaK; PFAM: Heat shock protein 70; von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: DnaK protein (Heat shock protein), C-terminal region has VWA type A domain; PFAM: Hsp70 protein; von Willebrand factor type A domain.
  
  0.584
Isop_1358
KEGG: plm:Plim_0058 putative membrane bound transporter; SPTR: Putative uncharacterized protein.
       0.576
Isop_3239
ABC transporter related protein; COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterPro IPR017871: IPR003593: IPR003439: IPR017940; KEGG: psl:Psta_2756 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Probable toxin secretion ABC transporter ATP-binding protein; PFAM: ABC transporter.
   
   0.567
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.550
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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