STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1373Protein of unknown function DUF6 transmembrane; COGs: COG0697 Permease of the drug/metabolite transporter (DMT) superfamily; InterPro IPR000620; KEGG: scl:sce4294 DMT family permease; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Permease of the drug/metabolite transporter (DMT) superfamily; PFAM: EamA-like transporter family. (473 aa)    
Predicted Functional Partners:
Isop_2500
Peptidase M10A and M12B matrixin and adamalysin; InterPro IPR001818: IPR021190; KEGG: hwa:HQ1193A cell surface glycoprotein; PFAM: peptidase M10A and M12B matrixin and adamalysin; SPTR: Probable cell surface glycoprotein; PFAM: Matrixin.
  
     0.565
Isop_1432
Repeat-companion domain protein; InterPro IPR014338: IPR001611; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; PFAM: Leucine Rich Repeat; TIGRFAM: repeat-companion domain TIGR02996.
  
    0.498
Isop_2658
Metallophosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: ade:Adeh_0989 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
  
     0.455
Isop_0537
Repeat-companion domain protein; InterPro IPR003590: IPR014338; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; TIGRFAM: repeat-companion domain TIGR02996.
  
    0.443
Isop_0378
KEGG: reu:Reut_A1745 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.422
Isop_0507
Repeat-companion domain protein; InterPro IPR001611: IPR014338; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; PFAM: Leucine Rich Repeat; TIGRFAM: repeat-companion domain TIGR02996.
  
    0.422
Isop_0236
PDZ/DHR/GLGF domain protein; InterPro IPR001478: IPR001969; KEGG: rlt:Rleg2_1589 membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; PFAM: PDZ domain (Also known as DHR or GLGF).
  
 
   0.408
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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