| node1 | node2 | node1 annotation | node2 annotation | score |
| Isop_1375 | Isop_1376 | thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family. | UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Molybdopterin biosynthesis protein MoeB; PFAM: MoeZ/MoeB domain; ThiF family. | 0.978 |
| Isop_1375 | Isop_1377 | thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | 0.410 |
| Isop_1376 | Isop_1375 | UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Molybdopterin biosynthesis protein MoeB; PFAM: MoeZ/MoeB domain; ThiF family. | thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family. | 0.978 |
| Isop_1376 | Isop_1377 | UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Molybdopterin biosynthesis protein MoeB; PFAM: MoeZ/MoeB domain; ThiF family. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | 0.703 |
| Isop_1377 | Isop_1375 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family. | 0.410 |
| Isop_1377 | Isop_1376 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Molybdopterin biosynthesis protein MoeB; PFAM: MoeZ/MoeB domain; ThiF family. | 0.703 |
| Isop_1377 | Isop_1969 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | 0.902 |
| Isop_1377 | Isop_2249 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | KEGG: psl:Psta_1030 endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase. | 0.480 |
| Isop_1377 | Isop_2681 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: sal:Sala_1018 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family. | 0.480 |
| Isop_1377 | Isop_3201 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | Endonuclease/exonuclease/phosphatase; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: scl:sce4697 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/Exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family. | 0.480 |
| Isop_1377 | Isop_3226 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | FeS assembly ATPase SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR017871: IPR010230: IPR003593: IPR003439; KEGG: plm:Plim_2389 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC. | 0.759 |
| Isop_1377 | Isop_3227 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | Iron-regulated ABC transporter membrane component SufB; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231: IPR000825; KEGG: plm:Plim_2390 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB. | 0.729 |
| Isop_1377 | Isop_3228 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | SufBD protein; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: plm:Plim_2391 FeS assembly protein SufD; PFAM: SufBD protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1. | 0.735 |
| Isop_1377 | Isop_3230 | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: rmr:Rmar_0984 Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated domain. | 0.668 |
| Isop_1969 | Isop_1377 | Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | 0.902 |
| Isop_1969 | Isop_3226 | Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | FeS assembly ATPase SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR017871: IPR010230: IPR003593: IPR003439; KEGG: plm:Plim_2389 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC. | 0.855 |
| Isop_1969 | Isop_3227 | Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | Iron-regulated ABC transporter membrane component SufB; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231: IPR000825; KEGG: plm:Plim_2390 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB. | 0.791 |
| Isop_1969 | Isop_3228 | Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | SufBD protein; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: plm:Plim_2391 FeS assembly protein SufD; PFAM: SufBD protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1. | 0.772 |
| Isop_2249 | Isop_1377 | KEGG: psl:Psta_1030 endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | 0.480 |
| Isop_2681 | Isop_1377 | Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: sal:Sala_1018 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family. | Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. | 0.480 |