STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1397COGs: COG2721 Altronate dehydratase; InterPro IPR013974: IPR007392; KEGG: kra:Krad_0582 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; PRIAM: Galactarate dehydratase; SPTR: Altronate dehydratase; PFAM: SAF domain; D-galactarate dehydratase / Altronate hydrolase, C terminus. (547 aa)    
Predicted Functional Partners:
Isop_1054
COGs: COG3836 2 4-dihydroxyhept-2-ene-1 7-dioic acid aldolase; InterPro IPR005000; KEGG: plm:Plim_3155 2-dehydro-3-deoxyglucarate aldolase; PFAM: HpcH/HpaI aldolase; PRIAM: 4-hydroxy-2-oxovalerate aldolase; SPTR: 2-dehydro-3-deoxyglucarate aldolase; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
 
 
  0.683
Isop_3401
COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: psl:Psta_4168 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
 
  
 0.552
Isop_0676
COGs: COG3386 Gluconolactonase; InterPro IPR005511: IPR013658; KEGG: plm:Plim_3928 gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region-containing protein; PRIAM: Gluconolactonase; SPTR: Gluconolactonase (Precursor); PFAM: SMP-30/Gluconolaconase/LRE-like region.
 
   
 0.409
Isop_1396
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003661: IPR003594: IPR 004358; KEGG: plm:Plim_1346 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domai [...]
       0.403
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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