STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_1423COGs: COG1915 conserved hypothetical protein; InterPro IPR005239: IPR007545; KEGG: psl:Psta_3748 LOR/SDH bifunctional protein conserved domain protein; PFAM: LOR/SDH bifunctional protein conserved domain protein; SPTR: LOR/SDH bifunctional protein conserved domain protein; PFAM: LOR/SDH bifunctional enzyme conserved region; TIGRFAM: conserved hypothetical protein TIGR00300. (438 aa)    
Predicted Functional Partners:
Isop_3073
Amidinotransferase; COGs: COG1834 N-Dimethylarginine dimethylaminohydrolase; InterPro IPR003198; KEGG: psl:Psta_3749 amidinotransferase; PFAM: amidinotransferase; SPTR: Amidinotransferase; PFAM: Amidinotransferase.
  
  0.993
Isop_0123
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR002872: IPR015590; KEGG: psl:Psta_0870 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: 1-pyrroline-5 carboxylate dehydrogenase; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Belongs to the aldehyde dehydrogenase family.
 
  
  0.929
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
  0.900
Isop_1422
KEGG: ana:alr7298 hypothetical protein; SPTR: Alr7298 protein; TIGRFAM: NHPM bacteriocin system secretion protein.
 
     0.633
Isop_3402
COGs: COG2006 conserved hypothetical protein; InterPro IPR006311: IPR017909; KEGG: dma:DMR_13230 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF362); TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.543
Isop_1421
ABC transporter related protein; COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterProIPR003439: IPR017940: IPR005074: IPR001140: IPR 017871: IPR003593; KEGG: npu:Npun_F3763 ABC transporter related; PFAM: ABC transporter related; peptidase C39 bacteriocin processing; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: Peptidase C39 family; ABC transporter transmembrane region; ABC transporter; TIGRFAM: NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein; NHPM b [...]
       0.438
Isop_2656
Hypothetical protein; COGs: COG1029 Formylmethanofuran dehydrogenase subunit B; KEGG: plm:Plim_2299 formylmethanofuran dehydrogenase subunit B-like protein; SPTR: Formyltransferase/hydrolase complex subunit B.
  
     0.412
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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