Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Isop_1432Repeat-companion domain protein; InterPro IPR014338: IPR001611; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; PFAM: Leucine Rich Repeat; TIGRFAM: repeat-companion domain TIGR02996. (513 aa)    
Predicted Functional Partners:
Isop_0390
Hypothetical protein; InterPro IPR003590; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.773
Isop_2500
Peptidase M10A and M12B matrixin and adamalysin; InterPro IPR001818: IPR021190; KEGG: hwa:HQ1193A cell surface glycoprotein; PFAM: peptidase M10A and M12B matrixin and adamalysin; SPTR: Probable cell surface glycoprotein; PFAM: Matrixin.
  
     0.622
Isop_2646
Dual specificity protein phosphatase; InterPro IPR000387: IPR000340; KEGG: olu:OSTLU_7942 predicted protein; PFAM: Dual specificity protein phosphatase; SPTR: Predicted protein; PFAM: Dual specificity phosphatase, catalytic domain.
  
     0.508
Isop_1548
InterPro IPR000866; KEGG: nca:Noca_1643 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Putative uncharacterized protein; manually curated; PFAM: AhpC/TSA family.
  
     0.504
Isop_1373
Protein of unknown function DUF6 transmembrane; COGs: COG0697 Permease of the drug/metabolite transporter (DMT) superfamily; InterPro IPR000620; KEGG: scl:sce4294 DMT family permease; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Permease of the drug/metabolite transporter (DMT) superfamily; PFAM: EamA-like transporter family.
  
    0.498
Isop_1843
Hypothetical protein; KEGG: dgr:Dgri_GH24162 GH24162 gene product from transcript GH24162-RA; SPTR: Kinesin K39, putative (ISS).
  
     0.497
Isop_0265
Protein of unknown function DUF167; COGs: COG1872 conserved hypothetical protein; InterPro IPR003746; KEGG: scl:sce8156 hypothetical protein; PFAM: protein of unknown function DUF167; SPTR: UPF0235 protein DehlyDRAFT_1349; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: conserved hypothetical protein TIGR00251; Belongs to the UPF0235 family.
  
     0.452
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
     0.452
Isop_1001
InterPro IPR001129: IPR001446; KEGG: gvi:glr3057 glutathione S-transferase; PFAM: membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG); SPTR: Glr3057 protein; PFAM: MAPEG family.
  
     0.418
Isop_0005
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020476: IPR020084: IPR000086; KEGG: ngr:NAEGRDRAFT_49855 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: Hydrolase, NUDIX family protein; PFAM: NUDIX domain.
  
     0.403
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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