node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Isop_1438 | obg | Isop_1438 | Isop_1690 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.782 |
Isop_1438 | rplC | Isop_1438 | Isop_2079 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.759 |
Isop_1438 | rplK | Isop_1438 | Isop_0109 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.726 |
Isop_1438 | rplM | Isop_1438 | Isop_3167 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.731 |
Isop_1438 | rplN | Isop_1438 | Isop_2089 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.728 |
Isop_1438 | rplO | Isop_1438 | Isop_2098 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.762 |
Isop_1438 | rplQ | Isop_1438 | Isop_2105 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: mca:MCA2346 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17. | 0.731 |
Isop_1438 | rplU | Isop_1438 | Isop_1593 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.768 |
Isop_1438 | rsfS | Isop_1438 | Isop_0742 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.753 |
Isop_1438 | rsmG | Isop_1438 | Isop_2600 | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.786 |
obg | Isop_1438 | Isop_1690 | Isop_1438 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | 0.782 |
obg | rplC | Isop_1690 | Isop_2079 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.761 |
obg | rplK | Isop_1690 | Isop_0109 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.813 |
obg | rplM | Isop_1690 | Isop_3167 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.776 |
obg | rplN | Isop_1690 | Isop_2089 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.634 |
obg | rplO | Isop_1690 | Isop_2098 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.763 |
obg | rplQ | Isop_1690 | Isop_2105 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: mca:MCA2346 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17. | 0.800 |
obg | rplU | Isop_1690 | Isop_1593 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.913 |
obg | rsfS | Isop_1690 | Isop_0742 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.842 |
rplC | Isop_1438 | Isop_2079 | Isop_1438 | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006145: IPR006224; KEGG: psl:Psta_2843 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family. | 0.759 |