STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
Isop_1450dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888: IPR001509; KEGG: msl:Msil_2711 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (381 aa)    
Predicted Functional Partners:
Isop_1451
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.999
Isop_1452
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
Isop_3015
COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: bfo:BRAFLDRAFT_68401 hypothetical protein; PFAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase.
 
 
 0.984
Isop_2639
NAD-dependent epimerase/dehydratase; COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR001412: IPR001509; KEGG: gvi:glr3121 methionine adenosyltransferase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Glr3121 protein; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase.
 
 
0.954
Isop_2272
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR008089: IPR001509; KEGG: rmr:Rmar_1858 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family.
  
 
0.909
Isop_0060
Nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: psl:Psta_1357 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose deh [...]
  
  
 0.852
Isop_0054
Multi antimicrobial extrusion protein MatE; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002528; KEGG: gbm:Gbem_1791 polysaccharide biosynthesis protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
  
  
 0.761
Isop_0174
Hypothetical protein; KEGG: clj:CLJU_c05530 putative polysaccharide biosynthesis protein; SPTR: Membrane protein involved in the export of O-antigen and teichoic acid.
  
  
 0.761
Isop_1551
COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR001937; KEGG: nde:NIDE3393 galactose-1-phosphate uridylyltransferase; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1.
   
  
 0.655
Isop_0824
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: rrs:RoseRS_4077 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
 
  
 0.553
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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