Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1487Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: psl:Psta_4258 sulfatase; PFAM: sulfatase; SPTR: Arylsulfatase; PFAM: Sulfatase. (476 aa)    
Predicted Functional Partners:
Isop_1428
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: htu:Htur_3376 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase.
  
     0.773
Isop_3638
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: sli:Slin_1433 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.687
Isop_1488
Folate-binding protein YgfZ; COGs: COG0354 aminomethyltransferase related to GcvT; InterPro IPR017703: IPR006222; KEGG: psl:Psta_1957 folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); SPTR: Putative uncharacterized protein; TIGRFAM: folate-binding protein YgfZ; PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ; Belongs to the GcvT family.
       0.578
Isop_1845
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: psl:Psta_4609 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.425
Isop_0208
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: psl:Psta_1182 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.401
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.