Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1488Folate-binding protein YgfZ; COGs: COG0354 aminomethyltransferase related to GcvT; InterPro IPR017703: IPR006222; KEGG: psl:Psta_1957 folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); SPTR: Putative uncharacterized protein; TIGRFAM: folate-binding protein YgfZ; PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ; Belongs to the GcvT family. (388 aa)    
Predicted Functional Partners:
Isop_3663
Iron-sulfur cluster assembly accessory protein; COGs: COG0316 conserved hypothetical protein; InterPro IPR017870: IPR000361: IPR016092; KEGG: plm:Plim_2978 iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: Iron-sulfur cluster assembly accessory protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 
 0.829
Isop_1487
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: psl:Psta_4258 sulfatase; PFAM: sulfatase; SPTR: Arylsulfatase; PFAM: Sulfatase.
       0.578
Isop_1489
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
       0.516
Isop_3300
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043: IPR006366: IPR000878: IPR003754; KEGG: gme:Gmet_3235 uroporphyrinogen-III synthase/uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.430
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
     0.409
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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