STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
Isop_1503COGs: COG1613 ABC-type sulfate transport system periplasmic component; InterPro IPR005669; KEGG: gym:GYMC10_5202 sulfate ABC transporter, periplasmic sulfate-binding protein; SPTR: Sulfate ABC transporter, periplasmic sulfate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; TIGRFAM: sulfate/thiosulfate-binding protein. (365 aa)    
Predicted Functional Partners:
Isop_1501
Sulfate ABC transporter, inner membrane subunit; COGs: COG4208 ABC-type sulfate transport system permease component; InterPro IPR000515: IPR005667; KEGG: cya:CYA_0468 sulfate ABC transporter, permease protein CysW; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sulfate ABC transporter, permease protein CysW; TIGRFAM: sulfate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein CysW; sulfate ABC transporter, permease protein.
 
 
 0.998
Isop_1502
Sulfate ABC transporter, inner membrane subunit; COGs: COG0555 ABC-type sulfate transport system permease component; InterPro IPR000515: IPR005667; KEGG: hau:Haur_0258 sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Sulfate ABC transporter, inner membrane subunit; TIGRFAM: sulfate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein CysW; sulfate ABC transporter, permease protein; sulfate ABC [...]
 
 
 0.998
cysA
Sulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
 
 
 0.997
cysC
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate.
  
 
 0.988
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.799
Isop_1056
COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117: IPR006067: IPR006066; KEGG: psl:Psta_1330 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Sulfite reductase (NADPH); SPTR: Sulfite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase.
 
  
 0.616
Isop_1742
Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR001638: IPR010065; KEGG: tai:Taci_0574 polar amino acid ABC transporter, inner membrane subunit; PFAM: extracellular solute-binding protein family 3; binding-protein-dependent transport systems inner membrane component; SMART: extracellular solute-binding protein family 3; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent tra [...]
  
  
 0.477
Isop_1504
Glycosyl transferase family 39; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: psl:Psta_3676 glycosyl transferase family 39; PFAM: glycosyl transferase family 39; SPTR: Glycosyl transferase family 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
       0.468
Isop_1346
ABC transporter related protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439: IPR003593; KEGG: bmr:BMI_II322 spermidine/putrescine ABC transporter, ATP-binding protein, putative; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter; Belongs to the ABC transporter superfamily.
 
     0.442
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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