Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Isop_1548InterPro IPR000866; KEGG: nca:Noca_1643 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Putative uncharacterized protein; manually curated; PFAM: AhpC/TSA family. (141 aa)    
Predicted Functional Partners:
Isop_0390
Hypothetical protein; InterPro IPR003590; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.591
Isop_1888
KEGG: pkn:PKH_127070 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.518
Isop_1432
Repeat-companion domain protein; InterPro IPR014338: IPR001611; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; PFAM: Leucine Rich Repeat; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.504
Isop_2646
Dual specificity protein phosphatase; InterPro IPR000387: IPR000340; KEGG: olu:OSTLU_7942 predicted protein; PFAM: Dual specificity protein phosphatase; SPTR: Predicted protein; PFAM: Dual specificity phosphatase, catalytic domain.
  
     0.503
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.488
Isop_0537
Repeat-companion domain protein; InterPro IPR003590: IPR014338; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.485
Isop_0389
Repeat-companion domain protein; InterPro IPR014338; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.480
Isop_3082
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680: IPR019782: IPR017986: IPR019781; KEGG: hoh:Hoch_3099 serine/threonine protein kinase with WD40 repeats; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: WD domain, G-beta repeat.
  
     0.434
Isop_3202
Hypothetical protein; KEGG: ttu:TERTU_3103 putative type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.423
Isop_0820
Methyltransferase type 11; COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR013216; KEGG: nve:NEMVE_v1g164983 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Predicted protein; PFAM: Methyltransferase domain.
  
     0.406
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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