Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1553Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: dal:Dalk_3474 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58. (299 aa)    
Predicted Functional Partners:
Isop_1531
Von Willebrand factor type A; InterPro IPR002035: IPR013026; KEGG: dma:DMR_35140 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Tetratricopeptide TPR_2 repeat protein; manually curated; PFAM: von Willebrand factor type A domain.
 
  
 0.811
Isop_1975
InterPro IPR002035; KEGG: srm:SRM_02789 von Willebrand factor type A domain protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: von Willebrand factor type A domain protein; PFAM: von Willebrand factor type A domain.
 
    0.788
Isop_3570
Von Willebrand factor type A; InterPro IPR002035; KEGG: cte:CT2278 hypothetical protein; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; PFAM: von Willebrand factor type A domain.
 
    0.784
Isop_3543
Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881: IPR002035; KEGG: psl:Psta_2915 protein of unknown function DUF58; PFAM: protein of unknown function DUF58; SMART: von Willebrand factor type A; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58.
  
     0.755
Isop_2743
Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: psl:Psta_2130 protein of unknown function DUF58; PFAM: protein of unknown function DUF58; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58.
  
     0.740
Isop_1552
4-alpha-glucanotransferase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR015178: IPR004300: IPR015179; KEGG: psl:Psta_3212 4-alpha-glucanotransferase; PFAM: Domain of unknown function DUF1926; Domain of unknown function DUF1925; glycoside hydrolase family 57; PRIAM: 4-alpha-glucanotransferase; SPTR: Alpha-amylase; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926).
       0.543
Isop_3544
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703; KEGG: psl:Psta_2916 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: Putative uncharacterized protein; PFAM: ATPase family associated with various cellular activities (AAA).
 
    0.471
Isop_0908
KEGG: paa:Paes_2121 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.423
Isop_0412
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR003593: IPR016366; KEGG: psl:Psta_1557 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: MoxR protein; PFAM: ATPase family associated with various cellular activities (AAA).
 
    0.407
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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