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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Isop_1557Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789: IPR003607: IPR006674; KEGG: dak:DaAHT2_0731 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain. (410 aa)    
Predicted Functional Partners:
Isop_2980
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR004358: IPR 003661: IPR003594: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein [...]
 
 
 0.819
Isop_2913
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 004358: IPR001610: IPR003661: IPR003594: IPR013656: IPR013655; KEGG: rxy:Rxyl_2663 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Multi-sensor hyb [...]
 
 
 0.818
Isop_1153
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: dsa:Desal_1726 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Hpt sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.783
Isop_3271
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR008207: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid h [...]
 
 
0.777
Isop_0090
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000253: IPR000160; KEGG: afw:Anae109_4141 diguanylate cyclase; PFAM: GGDEF domain containing protein; Forkhead-associated protein; SMART: GGDEF domain containing protein; Forkhead-associated protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 0.758
Isop_1972
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...]
 
 
0.748
Isop_1931
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000253: IPR000160; KEGG: scl:sce8626 FHA domain-containing protein; PFAM: GGDEF domain containing protein; Forkhead-associated protein; SMART: GGDEF domain containing protein; Forkhead-associated protein; SPTR: FHA domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.722
Isop_2900
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR004358: IPR003018: IPR003661: IPR 003594; KEGG: sit:TM1040_1854 GAF sensor hybrid histidine kinase; PFAM: histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase A domain protein; GAF domain protein; ATP-binding region ATPase domain protein; SPTR: GAF sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain.
 
 0.699
Isop_3550
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR000253: IPR005829; KEGG: hoh:Hoch_5913 diguanylate cyclase; PFAM: GGDEF domain containing protein; Forkhead-associated protein; SMART: GGDEF domain containing protein; Forkhead-associated protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.693
Isop_3189
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR005467: IPR000700: IPR013656: IPR013655; KEGG: eba:ebA126 two-component sensor kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Two-component sensor kinase; TIGRFAM: PAS sensor pro [...]
 
 
 
 0.672
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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