STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1568Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: saq:Sare_4930 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (364 aa)    
Predicted Functional Partners:
Isop_0969
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.970
Isop_1566
COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase.
  
 0.969
Isop_0271
Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: plm:Plim_0149 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.925
Isop_1785
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.917
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.913
Isop_3498
COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060: IPR019845; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase.
  
 0.871
Isop_1565
Hydroxyneurosporene synthase; InterPro IPR010791; KEGG: cch:Cag_0393 hydroxyneurosporene synthase CrtC; PFAM: hydroxyneurosporene synthase; SPTR: Hydroxyneurosporene synthase; PFAM: Hydroxyneurosporene synthase (CrtC).
  
  
 0.800
Isop_1567
COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR008150: IPR014105: IPR002937; KEGG: hau:Haur_3185 zeta-phytoene desaturase; PFAM: amine oxidase; SPTR: Zeta-phytoene desaturase; TIGRFAM: phytoene desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase.
  
  
 0.794
Isop_0085
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005841: IPR005844: IPR005845: IPR005846: IPR 005843; KEGG: rba:RB9832 phosphomannomutase (pmm); PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase (Pmm); PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, [...]
 
   
 0.532
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
    0.426
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.