STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1623Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034: IPR018356: IPR014036; KEGG: psl:Psta_3278 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional regulator, DeoR family; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain. (281 aa)    
Predicted Functional Partners:
Isop_1019
PfkB domain protein; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611: IPR002173; KEGG: sth:STH1246 tagatose-6-phosphate kinase; PFAM: PfkB domain protein; SPTR: Tagatose-6-phosphate kinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family.
 
  
 0.905
Isop_1624
Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
       0.806
Isop_1109
PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: plm:Plim_0361 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.590
Isop_1625
Microcompartments protein; COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR020808: IPR000249; KEGG: psl:Psta_3280 microcompartments protein; PFAM: microcompartments protein; SPTR: Microcompartments protein; PFAM: BMC domain.
       0.574
Isop_1626
Microcompartments protein; COGs: COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR020808: IPR000249; KEGG: psl:Psta_3281 microcompartments protein; PFAM: microcompartments protein; SPTR: Ethanolamine utilization protein; PFAM: BMC domain.
       0.526
rbsA
Monosaccharide ABC transporter ATP-binding protein, CUT2 family; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
   
 0.498
Isop_1622
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: psl:Psta_2023 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophos [...]
       0.452
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
  
 0.435
Isop_3302
Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: plm:Plim_0780 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Sugar ABC transporter permease protein; PFAM: Branched-chain amino acid transport system / permease component.
 
   
 0.400
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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