STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1633Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: plm:Plim_1747 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain. (330 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.920
Isop_1634
COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557: IPR018177: IPR001236; KEGG: psl:Psta_3289 lactate/malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: L-lactate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; Belongs to the LDH/MDH superfamily.
   
 
 0.825
mtnA
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
  
 0.712
Isop_1630
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR012408: IPR015590; KEGG: plm:Plim_1751 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Ethanolamine utilization protein EutE; PFAM: Aldehyde dehydrogenase family.
 
   
 0.663
Isop_3440
Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485; KEGG: psl:Psta_3010 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: rhamnulokinase.
 
  
 0.633
Isop_1632
KEGG: psl:Psta_3287 ethanolamine utilization protein EutN/carboxysome structural protein CcmL; SPTR: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; PFAM: Ethanolamine utilisation protein EutN/carboxysome.
       0.619
Isop_2634
Hypothetical protein; COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; KEGG: dac:Daci_5642 ribulose-bisphosphate carboxylase; SPTR: Ribulose-bisphosphate carboxylase; PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain.
  
  
 0.607
Isop_0668
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.601
Isop_1631
COGs: COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein; InterPro IPR004992; KEGG: plm:Plim_1750 ethanolamine utilization protein EutN/carboxysome structural protein CcmL; PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; SPTR: Putative uncharacterized protein; PFAM: Ethanolamine utilisation protein EutN/carboxysome.
       0.563
xylB
Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485: IPR018483: IPR006000; KEGG: plm:Plim_0722 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulose kinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase.
 
  
 0.558
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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