STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1637COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR020472: IPR 017441: IPR008271: IPR019775: IPR020635: IPR002290: IPR001680:I PR017442: IPR019781; KEGG: tcu:Tcur_0419 serine/threonine protein kinase with WD40 repeats; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: Protein kinase domain; WD domain, G-beta repeat. (896 aa)    
Predicted Functional Partners:
Isop_3386
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: plm:Plim_2397 phosphoprotein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein phosphatase; PFAM: Protein phosphatase 2C.
 
 
 0.909
Isop_3004
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045: IPR010822; KEGG: psl:Psta_1567 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C.
 
 
 0.905
Isop_0501
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR002290: IPR017441: IPR008271: IPR 000719; KEGG: rba:RB5593 serine/threonine-protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; SPTR: Serine/threonine-protein kinase; PFAM: Protein kinase domain.
  
     0.766
Isop_1821
KEGG: plm:Plim_2849 tyrosine protein kinase; SPTR: Tyrosine protein kinase.
  
     0.599
Isop_2908
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: cag:Cagg_1601 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Histone deacetylase superfamily; PFAM: Histone deacetylase domain.
    
  0.546
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
  
 0.541
Isop_1638
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR017441: IPR 008271: IPR020635: IPR002290: IPR001680: IPR017442: IPR019781; KEGG: sro:Sros_7190 WD40 repeat-domain-containing protein-like protein; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: WD40 repeat-domain-containing protein-like protein; PFAM: Protein kinase domain; WD domain, G-beta repeat.
 
    
0.536
Isop_2585
InterPro IPR007412; KEGG: psl:Psta_4010 anti-sigma-28 factor, FlgM; PFAM: Anti-sigma-28 factor FlgM family protein; SPTR: Anti-sigma-28 factor, FlgM; TIGRFAM: Anti-sigma-28 factor FlgM family protein; PFAM: Anti-sigma-28 factor, FlgM; TIGRFAM: flagellar biosynthesis anti-sigma factor FlgM.
  
   0.521
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  0.487
Isop_2714
RNA procession exonuclease-like protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: rrs:RoseRS_1582 RNA procession exonuclease-like protein; SPTR: Exonuclease of the beta-lactamase fold involved in RNA processing-like protein; PFAM: Metallo-beta-lactamase superfamily.
    
  0.467
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.