Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1654Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR000834: IPR002469; KEGG: sus:Acid_5302 peptidase S9B dipeptidylpeptidase IV subunit; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: Peptidase S9B, dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region; Zinc carboxypeptidase. (1212 aa)    
Predicted Functional Partners:
Isop_1883
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28.
  
    0.683
Isop_1372
Dipeptidyl-peptidase 7; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.
  
     0.677
Isop_0972
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: nde:NIDE3566 putative peptidase; PFAM: peptidase M28; SPTR: Aminopeptidase; PFAM: Peptidase family M28.
  
    0.664
Isop_2602
Glutamyl peptidase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: ccs:CCNA_02753 aminoacyl peptidase; SPTR: Peptidase, S9A/B/C family, catalytic domain protein; PFAM: Prolyl oligopeptidase family.
  
     0.616
Isop_2303
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR001478: IPR017441: IPR003137: IPR007484; KEGG: psl:Psta_3192 peptidase M28; PFAM: peptidase M28; protease-associated PA domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Probable aminopeptidase; PFAM: PA domain; PDZ domain (Also known as DHR or GLGF); Peptidase family M28.
  
    0.609
Isop_2467
Protein of unknown function DUF885; COGs: COG4805 conserved hypothetical protein; InterPro IPR010281; KEGG: scl:sce6178 hypothetical protein; PFAM: protein of unknown function DUF885; SPTR: Putative uncharacterized protein; manually curated; PFAM: Bacterial protein of unknown function (DUF885).
  
    0.604
Isop_3282
Peptidase S41; COGs: COG4946 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system; InterPro IPR012393: IPR005151: IPR011659; KEGG: hoh:Hoch_5294 peptidase S41; PFAM: peptidase S41; WD40-like beta Propeller containing protein; SMART: peptidase S41; SPTR: Peptidase S41; PFAM: WD40-like Beta Propeller Repeat; Peptidase family S41.
  
     0.569
Isop_0608
Peptidase M14 carboxypeptidase A; InterPro IPR000834; KEGG: sti:Sthe_2480 hypothetical protein; PFAM: peptidase M14 carboxypeptidase A; SPTR: Putative uncharacterized protein; PFAM: Zinc carboxypeptidase.
  
     0.539
Isop_0484
Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1.
  
     0.528
Isop_1147
Amino acid/peptide transporter; COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR005279: IPR000109: IPR018456; KEGG: xal:XALc_Yp01 hypothetical amino acid/peptide transporter protein; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: Di-/tripeptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial.
  
    0.483
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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