Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1666Peptidase S41; COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151; KEGG: gau:GAU_1102 peptidase S41A family protein; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Peptidase S41A family protein; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc). (479 aa)    
Predicted Functional Partners:
Isop_2651
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734: IPR013026: IPR001440; KEGG: plm:Plim_4208 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Putative uncharacterized protein.
   
   0.605
Isop_1665
KEGG: gau:GAU_1101 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
   0.602
Isop_1667
Protein of unknown function UPF0047; COGs: COG0432 conserved hypothetical protein; InterPro IPR018356: IPR001602; KEGG: hoh:Hoch_6559 protein of unknown function UPF0047; PFAM: protein of unknown function UPF0047; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme.
       0.411
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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