Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Isop_1703KEGG: dac:Daci_1596 hypothetical protein; SPTR: Putative uncharacterized protein. (134 aa)    
Predicted Functional Partners:
Isop_1679
ABC transporter related protein; COGs: COG1117 ABC-type phosphate transport system ATPase component; InterProIPR000387: IPR003439: IPR017871: IPR016130: IPR 003593: IPR003595: IPR000340; KEGG: dac:Daci_1595 ABC transporter related; PFAM: ABC transporter related; Dual specificity protein phosphatase; SMART: AAA ATPase; Protein-tyrosine phosphatase, catalytic; SPTR: ABC transporter related; PFAM: ABC transporter; Dual specificity phosphatase, catalytic domain.
 
     0.680
Isop_0911
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018: IPR003661: IPR003594: IPR001789: IPR 005467: IPR004358; KEGG: tcx:Tcr_2068 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; response regulator receiver; SPTR: Sensory transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, D [...]
  
 
 0.621
Isop_3283
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003661: IPR003594: IPR001789: IPR 005467: IPR011110; KEGG: cya:CYA_1657 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensory box histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; R [...]
  
 
 0.597
Isop_1842
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: afw:Anae109_0804 multi-sensor signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
 
 0.485
Isop_3271
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR008207: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid h [...]
  
 
 0.443
Isop_1396
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003661: IPR003594: IPR 004358; KEGG: plm:Plim_1346 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domai [...]
  
 
 0.415
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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