Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Isop_1714COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR005673: IPR006059; KEGG: gvi:gll2034 phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Phosphate-binding protein; TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein; Belongs to the PstS family. (418 aa)    
Predicted Functional Partners:
Isop_1712
Phosphate ABC transporter membrane protein 2, PhoT family; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515: IPR005672; KEGG: pfs:PFLU3316 phosphate transport system permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate transport system permease protein; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.
 
 0.999
Isop_1713
Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.999
pstB-2
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.993
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.981
Isop_1679
ABC transporter related protein; COGs: COG1117 ABC-type phosphate transport system ATPase component; InterProIPR000387: IPR003439: IPR017871: IPR016130: IPR 003593: IPR003595: IPR000340; KEGG: dac:Daci_1595 ABC transporter related; PFAM: ABC transporter related; Dual specificity protein phosphatase; SMART: AAA ATPase; Protein-tyrosine phosphatase, catalytic; SPTR: ABC transporter related; PFAM: ABC transporter; Dual specificity phosphatase, catalytic domain.
  
 
 0.837
Isop_2760
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.718
Isop_1425
ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439: IPR003339: IPR017871: IPR003593; KEGG: tbi:Tbis_0515 cobalt ABC transporter ATPase subunit; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase; SPTR: Cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter; Cobalt transport protein.
    
 0.577
Isop_1742
Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR001638: IPR010065; KEGG: tai:Taci_0574 polar amino acid ABC transporter, inner membrane subunit; PFAM: extracellular solute-binding protein family 3; binding-protein-dependent transport systems inner membrane component; SMART: extracellular solute-binding protein family 3; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent tra [...]
    
 0.577
Isop_1972
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...]
  
  
 0.535
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.533
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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