Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1740NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: plm:Plim_1981 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: NADH:flavin oxidoreductase; PFAM: NADH:flavin oxidoreductase / NADH oxidase family. (488 aa)    
Predicted Functional Partners:
Isop_3158
Cyclic nucleotide-binding protein; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR017900: IPR018528: IPR018488: IPR002373: IPR 000595: IPR001041: IPR017896; KEGG: sus:Acid_4310 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ferredoxin; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
 
  
 0.509
Isop_2747
Esterase; KEGG: psl:Psta_2350 esterase; SPTR: Putative uncharacterized protein.
  
     0.493
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
    0.488
Isop_0779
KEGG: scl:sce7589 hypothetical protein; SPTR: Conserved hypothetical membrane protein.
   
    0.488
Isop_1739
KEGG: tra:Trad_2522 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.484
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.
  
     0.473
Isop_3096
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: psl:Psta_3252 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family.
  
     0.437
Isop_1182
COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: plm:Plim_1620 ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: Ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
   
  
 0.436
Isop_1554
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: psl:Psta_0370 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: RNA binding S1 domain protein; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
   
  
 0.436
Isop_1741
ABC transporter related protein; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: bpt:Bpet2495 putative glutamine ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative glutamine ABC transporter ATP-binding protein; PFAM: ABC transporter.
       0.434
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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