| node1 | node2 | node1 annotation | node2 annotation | score |
| Isop_0015 | Isop_1743 | Hypothetical protein; KEGG: mno:Mnod_6296 glycosyl transferase family 2; SPTR: Glycosyl transferase family 2. | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | 0.444 |
| Isop_0015 | Isop_2284 | Hypothetical protein; KEGG: mno:Mnod_6296 glycosyl transferase family 2; SPTR: Glycosyl transferase family 2. | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | 0.425 |
| Isop_0015 | Isop_2285 | Hypothetical protein; KEGG: mno:Mnod_6296 glycosyl transferase family 2; SPTR: Glycosyl transferase family 2. | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | 0.468 |
| Isop_0661 | Isop_1743 | Creatininase; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: psl:Psta_1670 creatininase; PFAM: Creatininase; SPTR: Putative uncharacterized protein; PFAM: Creatinine amidohydrolase. | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | 0.511 |
| Isop_1160 | Isop_1743 | Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734: IPR013026: IPR001440; KEGG: azl:AZL_f01560 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | 0.507 |
| Isop_1742 | Isop_1743 | Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR001638: IPR010065; KEGG: tai:Taci_0574 polar amino acid ABC transporter, inner membrane subunit; PFAM: extracellular solute-binding protein family 3; binding-protein-dependent transport systems inner membrane component; SMART: extracellular solute-binding protein family 3; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent tra [...] | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | 0.530 |
| Isop_1742 | Isop_1972 | Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR001638: IPR010065; KEGG: tai:Taci_0574 polar amino acid ABC transporter, inner membrane subunit; PFAM: extracellular solute-binding protein family 3; binding-protein-dependent transport systems inner membrane component; SMART: extracellular solute-binding protein family 3; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent tra [...] | COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...] | 0.555 |
| Isop_1743 | Isop_0015 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Hypothetical protein; KEGG: mno:Mnod_6296 glycosyl transferase family 2; SPTR: Glycosyl transferase family 2. | 0.444 |
| Isop_1743 | Isop_0661 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Creatininase; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: psl:Psta_1670 creatininase; PFAM: Creatininase; SPTR: Putative uncharacterized protein; PFAM: Creatinine amidohydrolase. | 0.511 |
| Isop_1743 | Isop_1160 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734: IPR013026: IPR001440; KEGG: azl:AZL_f01560 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | 0.507 |
| Isop_1743 | Isop_1742 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR001638: IPR010065; KEGG: tai:Taci_0574 polar amino acid ABC transporter, inner membrane subunit; PFAM: extracellular solute-binding protein family 3; binding-protein-dependent transport systems inner membrane component; SMART: extracellular solute-binding protein family 3; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent tra [...] | 0.530 |
| Isop_1743 | Isop_1744 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Hypothetical protein; InterPro IPR017909; KEGG: rfr:Rfer_1421 thiopurine S-methyltransferase; SPTR: Secreted protein. | 0.512 |
| Isop_1743 | Isop_1955 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: neu:NE1170 putative dihydroflavonol-4-reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase. | 0.477 |
| Isop_1743 | Isop_1972 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...] | 0.447 |
| Isop_1743 | Isop_2284 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | 0.565 |
| Isop_1743 | Isop_2285 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | 0.533 |
| Isop_1743 | Isop_2378 | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | Cobyrinic acid ac-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: psl:Psta_0392 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | 0.640 |
| Isop_1744 | Isop_1743 | Hypothetical protein; InterPro IPR017909; KEGG: rfr:Rfer_1421 thiopurine S-methyltransferase; SPTR: Secreted protein. | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | 0.512 |
| Isop_1955 | Isop_1743 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: neu:NE1170 putative dihydroflavonol-4-reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase. | Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. | 0.477 |
| Isop_1955 | Isop_2284 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: neu:NE1170 putative dihydroflavonol-4-reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase. | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | 0.731 |