Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Isop_1743Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI. (418 aa)    
Predicted Functional Partners:
Isop_2378
Cobyrinic acid ac-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: psl:Psta_0392 cobyrinic acid ac-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
 
 0.640
Isop_2284
Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH.
 
   
 0.565
Isop_2285
COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase.
 
     0.533
Isop_1742
Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515: IPR001638: IPR010065; KEGG: tai:Taci_0574 polar amino acid ABC transporter, inner membrane subunit; PFAM: extracellular solute-binding protein family 3; binding-protein-dependent transport systems inner membrane component; SMART: extracellular solute-binding protein family 3; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent tra [...]
 
   
 0.530
Isop_1744
Hypothetical protein; InterPro IPR017909; KEGG: rfr:Rfer_1421 thiopurine S-methyltransferase; SPTR: Secreted protein.
       0.512
Isop_0661
Creatininase; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: psl:Psta_1670 creatininase; PFAM: Creatininase; SPTR: Putative uncharacterized protein; PFAM: Creatinine amidohydrolase.
  
  
 0.511
Isop_1160
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734: IPR013026: IPR001440; KEGG: azl:AZL_f01560 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
 
 
 0.507
Isop_1955
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: neu:NE1170 putative dihydroflavonol-4-reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase.
  
    0.477
Isop_1972
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...]
  
  
 0.447
Isop_0015
Hypothetical protein; KEGG: mno:Mnod_6296 glycosyl transferase family 2; SPTR: Glycosyl transferase family 2.
  
     0.444
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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