STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nnrECarbohydrate kinase, YjeF related protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (272 aa)    
Predicted Functional Partners:
nnrD
Carbohydrate kinase, YjeF related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
  
 0.977
Isop_1517
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021: IPR001650: IPR014014: IPR000629: IPR 014001: IPR011545; KEGG: psl:Psta_1620 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
    
 0.760
Isop_0097
NUDIX hydrolase; InterPro IPR000086; KEGG: sus:Acid_0573 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain.
  
 0.656
Isop_0905
NUDIX hydrolase; InterPro IPR020476: IPR000086: IPR020084; KEGG: hut:Huta_0878 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
  
 0.656
Isop_1682
NUDIX hydrolase; InterPro IPR020084: IPR000086; KEGG: chu:CHU_2826 pyrophosphohydrolase related protein; PFAM: NUDIX hydrolase; SPTR: Pyrophosphohydrolase related protein; PFAM: NUDIX domain.
  
 0.656
Isop_2671
NUDIX hydrolase; InterPro IPR020084: IPR000086: IPR020476; KEGG: sti:Sthe_1370 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain.
  
 0.656
Isop_1787
YjeF-family domain-containing protein; COGs: COG0062 conserved hypothetical protein; InterPro IPR004443; KEGG: rxy:Rxyl_0802 YjeF-related protein-like protein; PFAM: YjeF-family domain-containing protein; SPTR: Carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; TIGRFAM: yjeF N-terminal region.
  
     0.644
Isop_2670
NAD-dependent formate dehydrogenase flavoprotein subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: mno:Mnod_8359 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F [...]
   
   0.634
Isop_3157
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: kfl:Kfla_2118 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase- [...]
   
   0.634
Isop_3181
Tex-like protein; COGs: COG2183 Transcriptional accessory protein; InterPro IPR006641: IPR003029: IPR018974: IPR018316; KEGG: plm:Plim_2413 RNA binding S1 domain protein; PFAM: Tex-like protein-like; Tubulin/FtsZ, 2-layer sandwich domain; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: Ribosomal protein S1-like RNA-binding domain; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region.
    
   0.534
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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