| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_1367 | Isop_1656 | Isop_1367 | Isop_1656 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: cpb:Cphamn1_2348 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Putative uncharacterized protein; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit. | 0.579 |
| Isop_1367 | xseB | Isop_1367 | Isop_1786 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.610 |
| Isop_1568 | Isop_1785 | Isop_1568 | Isop_1785 | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: saq:Sare_4930 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.917 |
| Isop_1568 | xseB | Isop_1568 | Isop_1786 | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: saq:Sare_4930 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.409 |
| Isop_1656 | Isop_1367 | Isop_1656 | Isop_1367 | COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: cpb:Cphamn1_2348 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Putative uncharacterized protein; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit. | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.579 |
| Isop_1656 | xseB | Isop_1656 | Isop_1786 | COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: cpb:Cphamn1_2348 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Putative uncharacterized protein; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.476 |
| Isop_1785 | Isop_1568 | Isop_1785 | Isop_1568 | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: saq:Sare_4930 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.917 |
| Isop_1785 | dxs | Isop_1785 | Isop_1784 | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.860 |
| Isop_1785 | xseA | Isop_1785 | Isop_0187 | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.489 |
| Isop_1785 | xseB | Isop_1785 | Isop_1786 | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.629 |
| Isop_1787 | xseB | Isop_1787 | Isop_1786 | YjeF-family domain-containing protein; COGs: COG0062 conserved hypothetical protein; InterPro IPR004443; KEGG: rxy:Rxyl_0802 YjeF-related protein-like protein; PFAM: YjeF-family domain-containing protein; SPTR: Carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; TIGRFAM: yjeF N-terminal region. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.442 |
| Isop_1940 | xseB | Isop_1940 | Isop_1786 | Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962: IPR005232; KEGG: psl:Psta_4402 ExsB family protein; PFAM: asparagine synthase; SPTR: ExsB family protein; manually curated; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.421 |
| Isop_2664 | xseB | Isop_2664 | Isop_1786 | KEGG: lma:LmjF34.0690 hypothetical protein; SPTR: Putative uncharacterized protein. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.922 |
| Isop_3675 | xseB | Isop_3675 | Isop_1786 | Transcriptional regulator, TraR/DksA family; COGs: COG1734 DnaK suppressor protein; InterPro IPR020458: IPR000962; KEGG: psl:Psta_2164 transcriptional regulator, TraR/DksA family; SPTR: Transcriptional regulator, TraR/DksA family; PFAM: Prokaryotic dksA/traR C4-type zinc finger. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.411 |
| dxs | Isop_1785 | Isop_1784 | Isop_1785 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.860 |
| dxs | xseB | Isop_1784 | Isop_1786 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.554 |
| xseA | Isop_1785 | Isop_0187 | Isop_1785 | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: alv:Alvin_0767 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.489 |
| xseA | xseB | Isop_0187 | Isop_1786 | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.993 |
| xseB | Isop_1367 | Isop_1786 | Isop_1367 | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.610 |
| xseB | Isop_1568 | Isop_1786 | Isop_1568 | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: saq:Sare_4930 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.409 |