| node1 | node2 | node1 annotation | node2 annotation | score |
| Isop_0668 | Isop_1798 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.422 |
| Isop_0968 | Isop_1798 | COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: psl:Psta_0097 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.907 |
| Isop_1797 | Isop_1798 | KEGG: plm:Plim_2486 hypothetical protein; SPTR: Putative uncharacterized protein. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.453 |
| Isop_1798 | Isop_0668 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.422 |
| Isop_1798 | Isop_0968 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: psl:Psta_0097 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family. | 0.907 |
| Isop_1798 | Isop_1797 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | KEGG: plm:Plim_2486 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.453 |
| Isop_1798 | Isop_1799 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | KEGG: psl:Psta_3977 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.615 |
| Isop_1798 | Isop_1800 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.576 |
| Isop_1798 | Isop_2254 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.407 |
| Isop_1798 | Isop_2658 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | Metallophosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: ade:Adeh_0989 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase. | 0.411 |
| Isop_1799 | Isop_1798 | KEGG: psl:Psta_3977 hypothetical protein; SPTR: Putative uncharacterized protein. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.615 |
| Isop_1799 | Isop_1800 | KEGG: psl:Psta_3977 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.808 |
| Isop_1799 | Isop_2254 | KEGG: psl:Psta_3977 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.563 |
| Isop_1800 | Isop_1798 | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.576 |
| Isop_1800 | Isop_1799 | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: psl:Psta_3977 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.808 |
| Isop_1800 | Isop_2254 | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.768 |
| Isop_1800 | Isop_2658 | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | Metallophosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: ade:Adeh_0989 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase. | 0.441 |
| Isop_2254 | Isop_1798 | KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: gob:Gobs_4045 CDP-diacylglycerol-cholineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-choline O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase. | 0.407 |
| Isop_2254 | Isop_1799 | KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: psl:Psta_3977 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.563 |
| Isop_2254 | Isop_1800 | KEGG: aba:Acid345_4727 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: psl:Psta_3976 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.768 |