STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1832COGs: COG1203 helicase; InterPro IPR013444: IPR006483; KEGG: hoh:Hoch_4850 CRISPR-associated helicase Cas3, Anaes-subtype; SPTR: CRISPR-associated helicase Cas3, Anaes-subtype; TIGRFAM: CRISPR-associated helicase Cas3, Anaes-subtype; CRISPR-associated HD domain protein; TIGRFAM: CRISPR-associated endonuclease Cas3-HD; CRISPR-associated helicase Cas3, Anaes-subtype. (1058 aa)    
Predicted Functional Partners:
Isop_1834
CRISPR-associated protein, Csx4 family; InterPro IPR013403; KEGG: hoh:Hoch_4848 CRISPR-associated protein GSU0053; PFAM: CRISPR-associated protein GSU0053; SPTR: CRISPR-associated protein GSU0053; PFAM: CRISPR-associated protein GSU0053 (Cas_GSU0053); TIGRFAM: CRISPR-associated protein, GSU0053 family, N-terminal domain.
 
    0.949
Isop_1833
CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein, GSU0054 family.
 
    0.948
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.881
Isop_1831
KEGG: hoh:Hoch_4851 hypothetical protein; SPTR: Putative uncharacterized protein.
      0.796
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.794
Isop_0512
CRISPR-associated protein, GSU0054; InterPro IPR019089; KEGG: hoh:Hoch_4849 hypothetical protein; PFAM: CRISPR-associated protein, GSU0054; SPTR: Putative uncharacterized protein; manually curated; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054).
 
    0.784
Isop_3202
Hypothetical protein; KEGG: ttu:TERTU_3103 putative type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.733
Isop_0537
Repeat-companion domain protein; InterPro IPR003590: IPR014338; KEGG: hau:Haur_4051 hypothetical protein; SPTR: Leucine-rich repeat-containing protein typical subtype; TIGRFAM: repeat-companion domain protein; TIGRFAM: repeat-companion domain TIGR02996.
  
     0.722
Isop_2419
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR003587: IPR006530: IPR006141; KEGG: plm:Plim_1036 AmoP; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: AmoP; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).
  
     0.714
Isop_0601
KEGG: sus:Acid_4318 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.705
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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