Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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Isop_1854Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: aac:Aaci_2618 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. (333 aa)    
Predicted Functional Partners:
xylA
COGs: COG2115 Xylose isomerase; InterPro IPR001998: IPR013452: IPR012307; KEGG: psl:Psta_4262 xylose isomerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Xylose isomerase; SPTR: Xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; Belongs to the xylose isomerase family.
    
  0.900
Isop_0201
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: ttr:Tter_1808 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.763
Isop_3114
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR006311: IPR017909: IPR019546: IPR000683; KEGG: plm:Plim_3765 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Twin-arginine translocation pathway, signal sequence, subgroup; SPTR: Oxidoreductase domain protein; PFAM: TAT (twin-arginine translocation) pathway signal sequence; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.756
Isop_1887
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311: IPR017909; KEGG: rsl:RPSI07_2135 putative oxidoreductase; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.745
Isop_0714
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterProIPR000683: IPR004104: IPR006311: IPR017909: IPR 017970; KEGG: sus:Acid_3950 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.678
Isop_0752
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: plm:Plim_0917 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Similar to 1-carboxy-3-chloro-3,4-dihydroxycyclohexa-1, 5-diene dehydrogenase; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.593
Isop_2337
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: psl:Psta_3890 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Probable NADH-dependent dyhydrogenase related protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
     0.530
Isop_3280
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683; KEGG: zpr:ZPR_3683 putative dehydrogenase and relate protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.473
Isop_0502
Galactokinase; COGs: COG0153 Galactokinase; InterProIPR019539: IPR006204: IPR013750: IPR000705: IPR 006203: IPR006206; KEGG: rrs:RoseRS_3819 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
  
   0.406
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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