STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1883Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28. (531 aa)    
Predicted Functional Partners:
Isop_1654
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR000834: IPR002469; KEGG: sus:Acid_5302 peptidase S9B dipeptidylpeptidase IV subunit; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A; SPTR: Peptidase S9B, dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region; Zinc carboxypeptidase.
  
    0.684
Isop_2231
COGs: COG0308 Aminopeptidase N; KEGG: rba:RB5627 aminopeptidase; SPTR: Putative aminopeptidase; PFAM: Peptidase family M1.
  
 
 
 0.682
Isop_3003
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: rmr:Rmar_0089 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
  
     0.622
Isop_3297
InterPro IPR000834; KEGG: sus:Acid_1533 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SPTR: Peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase.
  
     0.621
Isop_0088
Peptidase S9B dipeptidylpeptidase IV domain protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: hoh:Hoch_4258 peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: Peptidase S9B dipeptidylpeptidase IV domain protein; PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region.
  
    0.593
Isop_1147
Amino acid/peptide transporter; COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR005279: IPR000109: IPR018456; KEGG: xal:XALc_Yp01 hypothetical amino acid/peptide transporter protein; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: Di-/tripeptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial.
 
 
   0.541
Isop_1882
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR001440: IPR020635: IPR002290: IPR 019734: IPR002151: IPR017441: IPR008271: IPR000719: IPR013026; KEGG: aba:Acid345_2310 TPR repeat-containing serine/threonin protein kinase; PFAM: Serine/threonine-protein kinase-like domain; Tetratricopeptide TPR_1 repeat-containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Tetratricopeptide repeat; SPTR: Putative serine/threonine protein kinase; PFAM: Protein kinase domain.
   
 0.502
Isop_0484
Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR015211; KEGG: amc:MADE_03140 putative cold-active aminopeptidase; secreted using a signal peptide; PFAM: Peptidase M1 membrane alanine aminopeptidase; Leukotriene A4 hydrolase; SPTR: Peptidase M1 membrane alanine aminopeptidase; PFAM: Leukotriene A4 hydrolase, C-terminal; Peptidase family M1.
  
 
 
 0.501
Isop_0183
WD40-like beta Propeller containing protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011659; KEGG: mxa:MXAN_6601 S9C family peptidase; PFAM: WD40-like beta Propeller containing protein; SPTR: Prolyl oligopeptidase family protein; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.
  
    0.493
Isop_2258
Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: scl:sce3068 putative secreted protein; PFAM: Amidohydrolase 3; SPTR: Putative lipoprotein; PFAM: Amidohydrolase family.
  
     0.475
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.