Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1888KEGG: pkn:PKH_127070 hypothetical protein; SPTR: Putative uncharacterized protein. (111 aa)    
Predicted Functional Partners:
Isop_1889
Hypothetical protein.
       0.528
Isop_1548
InterPro IPR000866; KEGG: nca:Noca_1643 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Putative uncharacterized protein; manually curated; PFAM: AhpC/TSA family.
  
     0.518
Isop_0820
Methyltransferase type 11; COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR013216; KEGG: nve:NEMVE_v1g164983 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Predicted protein; PFAM: Methyltransferase domain.
  
     0.505
Isop_3264
KEGG: mar:MAE_47620 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Dynamin family.
  
     0.496
Isop_2034
KEGG: cyh:Cyan8802_2208 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.486
Isop_2510
Peptidase M10A and M12B matrixin and adamalysin; InterPro IPR001818: IPR021190: IPR006026; KEGG: nml:Namu_5076 serine/threonine protein kinase; PFAM: peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase; SPTR: Serine/threonine protein kinase; PFAM: Matrixin; TIGRFAM: conserved repeat domain.
  
     0.416
Isop_1614
Na-Ca exchanger/integrin-beta4; InterPro IPR006118: IPR003644; KEGG: mpd:MCP_2796 hypothetical protein; PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; SPTR: Probable aggregation factor core protein MAFp3, isoform C; PFAM: Calx-beta domain.
  
     0.408
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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