Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1914COGs: COG3375 conserved hypothetical protein; KEGG: tpe:Tpen_1785 hypothetical protein; SPTR: Putative uncharacterized protein. (304 aa)    
Predicted Functional Partners:
Isop_1915
Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933: IPR011650: IPR017150: IPR001261; KEGG: cag:Cagg_3807 peptidase M20; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Peptidase M20; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.
 
     0.894
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
     0.780
Isop_1916
Protein of unknown function DUF420; COGs: COG1999 Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems; InterPro IPR003782: IPR007352: IPR017936; KEGG: plm:Plim_0216 protein of unknown function DUF420; PFAM: protein of unknown function DUF420; electron transport protein SCO1/SenC; SPTR: Putative uncharacterized protein; PFAM: SCO1/SenC; Protein of unknown function (DUF420).
       0.542
Isop_0256
Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: rba:RB10855 muconate cycloisomerase I; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: Muconate cycloisomerase I; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain.
 
     0.483
Isop_1913
Metallophosphoesterase; InterPro IPR004843; KEGG: sli:Slin_6603 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
       0.453
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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