STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1916Protein of unknown function DUF420; COGs: COG1999 Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems; InterPro IPR003782: IPR007352: IPR017936; KEGG: plm:Plim_0216 protein of unknown function DUF420; PFAM: protein of unknown function DUF420; electron transport protein SCO1/SenC; SPTR: Putative uncharacterized protein; PFAM: SCO1/SenC; Protein of unknown function (DUF420). (369 aa)    
Predicted Functional Partners:
Isop_0868
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 0.925
Isop_0870
COGs: COG1612 Uncharacterized protein required for cytochrome oxidase assembly; KEGG: rba:RB11934 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Cytochrome oxidase assembly protein.
 
 0.924
Isop_0869
COGs: COG0843 Heme/copper-type cytochrome/quinol oxidase subunit 1; InterPro IPR000883; KEGG: psl:Psta_2929 cytochrome-c oxidase; PFAM: cytochrome c oxidase subunit I; SPTR: Cytochrome c oxidase subunit I; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
 
 
 0.768
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
  
 0.714
Isop_0872
Cytochrome-c oxidase; COGs: COG1845 Heme/copper-type cytochrome/quinol oxidase subunit 3; InterPro IPR000298: IPR020606; KEGG: hwa:HQ2352A cytochrome-C-like terminal oxidase, subunit III; PFAM: cytochrome c oxidase subunit III; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome-c-like terminal oxidase, subunit III; PFAM: Cytochrome c oxidase subunit III.
 
  
 0.631
Isop_1915
Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933: IPR011650: IPR017150: IPR001261; KEGG: cag:Cagg_3807 peptidase M20; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Peptidase M20; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.
       0.623
Isop_1914
COGs: COG3375 conserved hypothetical protein; KEGG: tpe:Tpen_1785 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.542
Isop_0783
COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896; KEGG: ote:Oter_3934 Fe-S-cluster-containing hydrogenase components 1-like protein; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit.
 
   
 0.513
Isop_0577
Redoxin domain protein; InterPro IPR013740: IPR017936; KEGG: shn:Shewana3_1881 redoxin domain-containing protein; PFAM: Redoxin domain protein; SPTR: Thioredoxin-like protein; PFAM: AhpC/TSA family.
  
   0.508
Isop_3158
Cyclic nucleotide-binding protein; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR017900: IPR018528: IPR018488: IPR002373: IPR 000595: IPR001041: IPR017896; KEGG: sus:Acid_4310 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ferredoxin; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
  
 0.491
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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