Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_1930Alpha/beta hydrolase fold protein; COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: lic:LIC11875 putative hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: Putative hydrolase; PFAM: ab-hydrolase associated lipase region; alpha/beta hydrolase fold. (425 aa)    
Predicted Functional Partners:
Isop_2670
NAD-dependent formate dehydrogenase flavoprotein subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: mno:Mnod_8359 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F [...]
   
   0.916
Isop_3157
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: kfl:Kfla_2118 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase- [...]
   
   0.916
Isop_2736
KEGG: mxa:MXAN_5625 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.723
Isop_1461
Hypothetical protein; KEGG: mca:MCA2974 PKD domain-containing protein; SPTR: PKD domain protein.
  
     0.718
Isop_2653
Hypothetical protein; COGs: COG3387 Glucoamylase and related glycosyl hydrolase; KEGG: tjr:TherJR_2725 glycoside hydrolase 15-related protein; SPTR: Glycoside hydrolase 15-related protein.
  
     0.716
Isop_1520
InterPro IPR019734: IPR013026: IPR001440; KEGG: dak:DaAHT2_1784 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein.
 
 
   0.708
Isop_3495
Hypothetical protein; KEGG: mtp:Mthe_1626 periplasmic copper-binding; SPTR: Putative lipoprotein.
  
     0.705
Isop_0835
Hypothetical protein; COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; KEGG: hau:Haur_0806 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
  
     0.700
Isop_2275
InterPro IPR001623; KEGG: tcu:Tcur_1396 fibronectin type III domain protein; PFAM: heat shock protein DnaJ domain protein; SPTR: Fibronectin type III domain protein.
  
     0.695
Isop_1081
KEGG: eba:ebB145 acyl carrier protein; SPTR: Predicted acyl carrier protein; PFAM: Phosphopantetheine attachment site.
 
 
   0.692
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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