STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_1946COGs: COG0349 Ribonuclease D; InterPro IPR002562: IPR002121: IPR006292; KEGG: plm:Plim_0672 ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain protein; PRIAM: Ribonuclease D; SMART: 3'-5' exonuclease; HRDC domain protein; SPTR: Ribonuclease D; TIGRFAM: ribonuclease D; PFAM: HRDC domain; 3'-5' exonuclease; TIGRFAM: ribonuclease D. (396 aa)    
Predicted Functional Partners:
rnr
VacB and RNase II family 3'-5' exoribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.910
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
   
 0.905
Isop_2789
ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterProIPR014021: IPR001650: IPR014001: IPR007502: IPR 013689: IPR010225; KEGG: psl:Psta_3120 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase domain protein; helicase-associated domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpB.
  
  0.871
Isop_1407
COGs: COG0430 RNA 3'-terminal phosphate cyclase; InterPro IPR000228; KEGG: tgr:Tgr7_1692 RNA 3'-phosphate cyclase; PFAM: RNA 3'-terminal phosphate cyclase; PRIAM: RNA-3'-phosphate cyclase; SPTR: RNA 3'-phosphate cyclase; PFAM: RNA 3'-terminal phosphate cyclase; TIGRFAM: RNA 3'-phosphate cyclase.
   
  0.868
Isop_1182
COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: plm:Plim_1620 ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: Ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
 0.842
Isop_1554
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: psl:Psta_0370 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: RNA binding S1 domain protein; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
 0.823
rpsD
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.810
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.792
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
 0.786
Isop_1517
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021: IPR001650: IPR014014: IPR000629: IPR 014001: IPR011545; KEGG: psl:Psta_1620 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 0.756
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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