STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_1960ATP-dependent Clp protease adaptor protein ClpS; COGs: COG2127 conserved hypothetical protein; InterPro IPR003769; KEGG: rxy:Rxyl_2055 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS. (124 aa)    
Predicted Functional Partners:
Isop_0483
COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331: IPR002177; KEGG: psl:Psta_1613 ferritin Dps family protein; PFAM: Ferritin Dps family protein; SPTR: Ferritin Dps family protein; PFAM: Ferritin-like domain; Belongs to the Dps family.
   
 
 0.815
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.747
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.745
Isop_0962
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593: IPR001943: IPR004176: IPR003959: IPR 013093: IPR019489: IPR001270: IPR018368; KEGG: plm:Plim_0603 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA [...]
  
 
 0.745
Isop_0788
Abortive infection protein; InterPro IPR003675; KEGG: rba:RB10877 hypothetical protein; PFAM: Abortive infection protein; SPTR: Putative uncharacterized protein; PFAM: CAAX amino terminal protease family.
 
    0.606
Isop_2160
Secretion protein HlyD family protein; InterPro IPR003997: IPR006143; KEGG: rba:RB10473 alkaline protease secretion protein AprE; PFAM: secretion protein HlyD family protein; SPTR: Similar to alkaline proteinase secretion protein aprE.
  
     0.470
argD
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR004636; KEGG: psl:Psta_2678 acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
    
   0.466
aat
leucyl/phenylalanyl-tRNA/protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
 
  
 0.445
Isop_0862
KEGG: psl:Psta_4371 hypothetical protein; SPTR: Probable serine proteinase, subtilase family protein.
  
     0.443
Isop_1961
Hypothetical protein; KEGG: mcc:705891 Rho guanine nucleotide exchange factor (GEF) 5; SPTR: Small Conductance Mechanosensitive ion Channel family protein.
       0.443
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.