STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_1968COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ace:Acel_1138 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurases, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily. (469 aa)    
Predicted Functional Partners:
Isop_1969
Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
 
 
 0.975
Isop_3226
FeS assembly ATPase SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR017871: IPR010230: IPR003593: IPR003439; KEGG: plm:Plim_2389 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
 
  
 0.923
Isop_3227
Iron-regulated ABC transporter membrane component SufB; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231: IPR000825; KEGG: plm:Plim_2390 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.
 
 
 0.918
Isop_3228
SufBD protein; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: plm:Plim_2391 FeS assembly protein SufD; PFAM: SufBD protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1.
 
 
 0.918
Isop_0020
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 
  0.917
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.907
Isop_3230
COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: rmr:Rmar_0984 Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated domain.
  
 
 0.668
Isop_3232
Protein of unknown function DUF59; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: plm:Plim_2392 protein of unknown function DUF59; PFAM: protein of unknown function DUF59; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF59.
 
  
 0.511
Isop_2249
KEGG: psl:Psta_1030 endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase.
    
   0.480
Isop_2681
Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: sal:Sala_1018 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family.
    
   0.480
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.